Each Asacol HD delayed-release tablet for oral
administration contains 800 mg of mesalamine, an antiinflammatory drug. Asacol
HD delayed-release tablets have an outer protective coat consisting of a
combination of acrylic based resins, Eudragit S (methacrylic acid copolymer B,
NF) and Eudragit L (methacrylic acid copolymer A, NF). The inner coat consists
of an acrylic based resin, Eudragit S, which dissolves at pH 7 or greater,
releasing mesalamine in the terminal ileum and beyond for topical
anti-inflammatory action in the colon. Mesalamine (also referred to as
5-aminosalicylic acid or 5-ASA) has the chemical name 5-amino-2-hydroxybenzoic
acid; its structural formula is:
Molecular Weight : 153.1
Molecular Formula : C7H7NO3
Inactive Ingredients: Each tablet contains colloidal silicon dioxide,
dibutyl phthalate, edible black ink, ferric oxide red, ferric oxide yellow, lactose monohydrate, magnesium stearate, methacrylic acid copolymer B (Eudragit
S), methacrylic acid copolymer A (Eudragit L), polyethylene glycol, povidone, sodium starch glycolate, and talc.
What are the possible side effects of mesalamine oral (Apriso, Asacol, Asacol HD, Lialda, Pentasa)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking mesalamine and call your doctor at once if you have a serious side effect such as:
- severe stomach pain, cramping, fever, headache, and bloody diarrhea.
Less serious side effects may include:
- mild nausea, vomiting, stomach cramps, diarrhea, gas;
- fever, sore throat, or other flu symptoms;
- headache or...
Read All Potential Side Effects and See Pictures of Asacol HD »
Last reviewed on RxList: 10/23/2009
This monograph has been modified to include the generic and brand name in many instances.