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LATISSE®
(bimatoprost) Ophthalmic Solution

DRUG DESCRIPTION

LATISSE® (bimatoprost ophthalmic solution) 0.03% is a synthetic prostaglandin analog. Its chemical name is (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1pentenyl]cyclopentyl] -N-ethyl-5-heptenamide, and its molecular weight is 415.58. Its molecular formula is C25H37NO4. Its chemical structure is:

LATISSE® (bimatoprost) Structural Formula Illustration

Bimatoprost is a powder, which is very soluble in ethyl alcohol and methyl alcohol and slightly soluble in water. LATISSE® is a clear, isotonic, colorless, sterile ophthalmic solution with an osmolality of approximately 290 mOsmol/kg.

Contains: Active: bimatoprost 0.3 mg/mL; Preservative: benzalkonium chloride 0.05 mg/mL; Inactives: sodium chloride; sodium phosphate, dibasic; citric acid; and purified water. Sodium hydroxide and/or hydrochloric acid may be added to adjust pH. The pH during its shelf life ranges from 6.8 - 7.8.

What are the precautions when taking bimatoprost ophthalmic solution 0.03% for hypotrichosis (Latisse)?

Before using bimatoprost, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as latanoprost, travoprost); or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye pressure problems (such as glaucoma), other eye problems (such as macular edema, iritis, uveitis, lens extraction/aphakia).

If you develop a new eye condition (such as infection, eye surgery, eye injury) while using this medication, discuss with your doctor whether you should start using a new bottle.

If...

Read All Potential Precautions of Latisse »

Last reviewed on RxList: 4/11/2012
This monograph has been modified to include the generic and brand name in many instances.