VICTRELIS (boceprevir) is an inhibitor of the hepatitis C
virus (HCV) non-structural protein 3 (NS3) serine protease.
Boceprevir has the following chemical name:
azabicyclo[3.1.0]hexan-2(S)-carboxamide. The molecular formula is C27H45N5O5
and its molecular weight is 519.7. Boceprevir has the following structural
Boceprevir is manufactured as an approximately equal
mixture of two diastereomers. Boceprevir is a white to off-white amorphous
powder. It is freely soluble in methanol, ethanol and isopropanol and slightly soluble
VICTRELIS 200 mg capsules are available as hard gelatin
capsules for oral administration. Each capsule contains 200 mg of boceprevir
and the following inactive ingredients: sodium lauryl sulfate, microcrystalline
cellulose, lactose monohydrate, croscarmellose sodium, pre-gelatinized starch,
and magnesium stearate. The red capsule cap consists of gelatin, titanium
dioxide, D&C Yellow #10, FD&C Blue #1, and FD&C Red #40. The yellow
capsule body contains gelatin, titanium dioxide, D&C Yellow #10, FD&C
Red #40, and FD&C Yellow #6. The capsule is printed with red and yellow
ink. The red ink contains shellac and red iron oxide, while the yellow ink
consists of shellac, titanium dioxide, povidone and D&C Yellow #10 Aluminum
What are the possible side effects of boceprevir (Victrelis)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using boceprevir and call your doctor at once if you have a serious side effect such as:
- pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or
- fever, chills, body aches, flu symptoms, sores in your mouth and throat.
Less serious side effects may include:
- feeling weak, tired, or irritable;
- headache, dizziness;
Read All Potential Side Effects and See Pictures of Victrelis »
Last reviewed on RxList: 11/19/2012
This monograph has been modified to include the generic and brand name in many instances.