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Cefadroxil
((cefadroxil hemihydrate) Tablet, Film Coated

Cefadroxil
(cefadroxil hemihydrate) Capsule

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefadroxil (cefadroxil hemihydrate) Tablets and Cefadroxil (cefadroxil hemihydrate) Capsules and other antibacterial drugs, Cefadroxil (cefadroxil hemihydrate) Tablets and Cefadroxil (cefadroxil hemihydrate) Capsules should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

DRUG DESCRIPTION

Cefadroxil (cefadroxil hemihydrate), USP (hemihydrate) is a semisynthetic cephalosporin antibiotic intended for oral administration. It is white to off-white crystalline powder. It is slightly soluble in water and it is acid-stable. It is chemically designated as 5-Thia-1-azabicyclo [4.2.0] oct-2-ene-2-carboxylic acid, 7-[[amino (4-hydroxyphenyl) acetyl] amino]-3- methyl-8-oxo-, hemihydrate, [6R-[6α, 7β (R*)]]-. It has the formula C16H17N3O5S•½ H2O and the molecular weight of 372.39. It has the following structural formula:

cefadroxil (cefadroxil hemihydrate) structural formula illustration

Each film coated tablet for oral administration contains Cefadroxil (cefadroxil hemihydrate) hemihydrate equivalent to 1 gram cefadroxil (cefadroxil hemihydrate). In addition, each tablet contains the following inactive ingredients: croscarmellose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, monosodium citrate, polyethylene glycol, talc and titanium dioxide.

Each capsule for oral administration contains Cefadroxil (cefadroxil hemihydrate) hemihydrate equivalent to 500 mg cefadroxil (cefadroxil hemihydrate). In addition, each capsule contains the following inactive ingredients: magnesium stearate and pregelatinized starch.

The capsule shell also contains D&C yellow no. 10, FD&C blue no. 1, FD&C red no. 40, gelatin and titanium dioxide.

The imprinting ink also contains D&C yellow no. 10 aluminum lake, FD&C blue no. 1 aluminum lake, FD&C blue no. 2 aluminum lake, FD&C red no. 40 aluminum lake, pharmaceutical glaze, propylene glycol and synthetic black iron oxide.

Last reviewed on RxList: 7/31/2007
This monograph has been modified to include the generic and brand name in many instances.