The active component of ALVESCO 80 mcg Inhalation
Aerosol, and ALVESCO 160 mcg Inhalation Aerosol is ciclesonide, a
non-halogenated glucocorticoid having the chemical name
The empirical formula is C32H44O7 and its
molecular weight is 540.7. Its structural formula is as follows:
Ciclesonide is a white to
yellow-white powder. It is soluble in dehydrated alcohol, acetone,
dichloromethane, and chloroform.
ALVESCO 80 mcg Inhalation
Aerosol and ALVESCO 160 mcg Inhalation Aerosol are pressurized, metered-dose
aerosol units fitted with a dose indicator. ALVESCO is intended for oral
inhalation only. Each unit contains a solution of ciclesonide in propellant
HFA-134a (1,1,1,2 tetrafluoroethane) and ethanol. After priming, ALVESCO 80 mcg
delivers 100 mcg from the valve and 80 mcg of ciclesonide from the actuator.
ALVESCO 160 mcg delivers 200 mcg from the valve and 160 mcg of ciclesonide from
the actuator. This product delivers 50 microliters (59.3 milligrams) of
solution as a fine particle mist from the valve with each actuation. The actual
amount of drug delivered to the lung may depend on patient factors, such as the
coordination between the actuation of the device and inspiration through the
delivery system. ALVESCO should be “primed” by actuating 3 times prior to using
the first dose from a new canister or when the inhaler has not been used for
more than 10 days. Avoid spraying in the eyes or face while priming ALVESCO.
What are the possible side effects of ciclesonide inhalation (Alvesco HFA)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- wheezing, choking, or other breathing problems after using this medication;
- sores or white patches in your mouth or throat;
- vision problems, such as tunnel vision or blurred vision; or
- worsening asthma symptoms.
Less serious side effects may include:
- unpleasant taste in your...
Read All Potential Side Effects and See Pictures of Alvesco »
Last reviewed on RxList: 1/14/2013
This monograph has been modified to include the generic and brand name in many instances.