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ACANYA Gel
(clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) For topical use

DRUG DESCRIPTION

ACANYA Gel (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) is a combination product with two active ingredients in an aqueous gel formulation. Clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.

The chemical name for clindamycin phosphate is Methyl 7-chloro­6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1­thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate). The structural formula for clindamycin phosphate is represented below:

Clindamycin phosphate:

Clindamycin phosphate Structural Formula Illustration

Molecular Formula: C18H34ClN2O8PS Molecular Weight: 504.97

Benzoyl peroxide is an antibacterial and keratolytic agent. The structural formula for benzoyl peroxide is represented below:

Benzoyl peroxide:

Benzoyl peroxide Structural Formula Illustration

Molecular Formula: C14H10O4 Molecular Weight: 242.23

ACANYA Gel (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) contains the following inactive ingredients: purified water, carbomer 980, propylene glycol, and potassium hydroxide. Each gram of ACANYA Gel (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) contains 1.2% of clindamycin phosphate which is equivalent to 1% clindamycin.

What are the possible side effects of benzoyl peroxide and clindamycin topical?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have any of these serious side effects:

  • severe redness, burning, stinging, or peeling of treated skin areas; or
  • diarrhea that is watery or bloody.

Less serious side effects may include:

  • mild burning or stinging;
  • itching or tingly feeling;
  • dryness or peeling of treated skin;...

Read All Potential Side Effects and See Pictures of Acanya Gel »

Last reviewed on RxList: 7/20/2010
This monograph has been modified to include the generic and brand name in many instances.