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Codeine
(sulfate) Tablets

DRUG DESCRIPTION

Chemically, codeine is Morphinan-6-ol,7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-(5a,6a)-, sulfate (2:1) (salt), trihydrate. Its empirical formula is C18H21NO3 and its molecular weight is 299.36.

Its structure is as follows:

Codeine sulfate Structural Formula Illustration

Each tablet contains 15, 30, or 60 mg of codeine sulfate and the following inactive ingredients: colloidal silicon dioxide, microcrystalline cellulose, pregelatinized starch, and stearic acid.

What are the possible side effects of codeine ()?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • slow heart rate, weak pulse, fainting, shallow breathing;
  • feeling like you might pass out;
  • confusion, agitation, hallucinations, unusual thoughts or behavior;
  • feelings of extreme happiness or sadness;
  • seizure (convulsions); or
  • problems with urination.

Less serious side effects include:

  • feeling...

Read All Potential Side Effects and See Pictures of Codeine Sulfate »

What are the precautions when taking codeine (Codeine Sulfate)?

Before taking codeine, tell your doctor or pharmacist if you are allergic to it; or to other narcotic pain medications (e.g., morphine, hydrocodone, oxycodone); or if you have any other allergies. This product may contain inactive ingredients (such as sulfites found in some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe breathing problems (e.g., respiratory depression, carbon dioxide retention), a certain bowel disease (paralytic ileus), severe infectious diarrhea (e.g., Clostridium difficile-associated diarrhea), intoxication with medications that can cause drowsiness...

Read All Potential Precautions of Codeine Sulfate »

Last reviewed on RxList: 5/26/2011
This monograph has been modified to include the generic and brand name in many instances.