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COGENTIN®
(benztropine mesylate) Injection

DRUG DESCRIPTION

Benztropine mesylate is a synthetic compound containing structural features found in atropine and diphenhydramine.

It is designated chemically as 8-azabicyclo[3.2.1] octane, 3-(diphenylmethoxy)-,endo, methanesulfonate. Its empirical formula is C21H25NO•CH4O3S, and its structural formula is:

Benztropine mesylate structural formula illustration

Benztropine mesylate is a crystalline white powder, very soluble in water, and has a molecular weight of 403.54. COGENTIN* (Benztropine Mesylate) is supplied as a sterile injection for intravenous and intramuscular use.

Each milliliter of the injection contains:

Benztropine mesylate ..........1 mg
Sodium chloride ...............9 mg
Water for injection q.s. . ....1 mL

What are the possible side effects of benztropine (Cogentin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • pounding heartbeats or fluttering in your chest;
  • feeling very weak;
  • feeling too weak to move;
  • confusion, hallucinations, unusual thoughts or behavior;
  • urinating less than usual or not at all;
  • severe constipation;
  • dry mouth that interferes with speech, swallowing, appetite, or...

Read All Potential Side Effects and See Pictures of Cogentin »

Last reviewed on RxList: 6/20/2007
This monograph has been modified to include the generic and brand name in many instances.