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DEMADEX®
(torsemide) Tablets

DRUG DESCRIPTION

DEMADEX (torsemide) is a diuretic of the pyridine-sulfonylurea class. Its chemical name is 1-isopropyl-3-[(4-m-toluidino-3-pyridyl) sulfonyl] urea and its structural formula is:

DEMADEX® (torsemide) Structural Formula Illustration

Its empirical formula is C16H20N4O3S, its pKa is 7.1, and its molecular weight is 348.43.

Torsemide is a white to off-white crystalline powder. The tablets for oral administration also contain lactose NF, crospovidone NF, povidone USP, microcrystalline cellulose NF, and magnesium stearate NF.

What are the possible side effects of torsemide

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using torsemide and call your doctor at once if you have a serious side effect such as:

  • dry mouth, thirst, nausea, vomiting;
  • feeling weak, drowsy, restless, or light-headed;
  • fast or uneven heartbeat;
  • muscle pain or weakness;
  • coughing up blood;
  • bloody or black, tarry stools; or
  • hearing loss.

Less serious side effects may include:

  • diarrhea or...

Read All Potential Side Effects and See Pictures of Demadex »

What are the precautions when taking torsemide (Demadex)?

Before taking torsemide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems, inability to make urine, gout.

If you have diabetes, torsemide may infrequently affect your blood sugar level. Check your blood sugar level regularly as directed and share the results with your doctor. Your doctor may need to adjust your diabetes medication or diet.

Torsemide may reduce the potassium level in your blood. Your doctor may instruct you to add potassium-rich foods to...

Read All Potential Precautions of Demadex »

Last reviewed on RxList: 8/27/2012
This monograph has been modified to include the generic and brand name in many instances.