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DOPRAM Injection
(doxapram hydrochloride) Injection, USP

NOT FOR USE IN NEONATES CONTAINS BENZYL ALCOHOL

DRUG DESCRIPTION

DOPRAM Injection (doxapram hydrochloride injection, USP) is a clear, colorless, sterile, non-pyrogenic, aqueous solution with pH 3.5 to 5, for intravenous administration.

Each 1 mL contains:

Doxapram Hydrochloride, USP ....................................... 20 mg
Benzyl Alcohol, NF (as preservative) ............................... 0.9%
Water for Injection, USP ........... … ................................. q.s.

Doxapram Injection is a respiratory stimulant.

Doxapram hydrochloride is a white to off-white, crystalline powder, sparingly soluble in water, alcohol and chloroform. Chemically, doxapram hydrochloride is 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone monohydrochloride, monohydrate.

The chemical structure is:

DOPRAM (doxapram hydrochloride) Structural Formula Illustration

C24H31ClN2O2•H2O........................M.W. 432.99

Last reviewed on RxList: 5/5/2009
This monograph has been modified to include the generic and brand name in many instances.