ELIQUIS (apixaban), a factor Xa (FXa) inhibitor, is
chemically described as
Its molecular formula is C25H25N5O4,
which corresponds to a molecular weight of 459.5. Apixaban has the following
Apixaban is a white to
pale-yellow powder. At physiological pH (1.2-6.8), apixaban does not ionize;
its aqueous solubility across the physiological pH range is ~0.04 mg/mL.
ELIQUIS tablets are available for oral administration in
strengths of 2.5 mg and 5 mg of apixaban with the following inactive
ingredients: anhydrous lactose, microcrystalline cellulose, croscarmellose
sodium, sodium lauryl sulfate, and magnesium stearate. The film coating
contains lactose monohydrate, hypromellose, titanium dioxide, triacetin, and
yellow iron oxide (2.5 mg tablets) or red iron oxide (5 mg tablets).
Last reviewed on RxList: 1/10/2013
This monograph has been modified to include the generic and brand name in many instances.