Ismelin, guanethidine monosulfate USP, is an antihypertensive, available as tablets of 10 mg and 25 mg for oral administration. Each 10-mg and 25-mg tablet contains guanethidine monosulfate USP equivalent to 10 mg and 25 mg of guanethidine sulfate USP. Its chemical name is [2-(hexahydro-1(2H)-azocinyl)ethyl] guanidine sulfate 1:1.
Guanethidine monosulfate USP is a white to off-white crystalline powder with a molecular weight of 296.38. It is very soluble in water, sparingly soluble in alcohol, and practically insoluble in chloroform.
Inactive Ingredients: Calcium stearate, colloidal silicon dioxide D&C Yellow No. 10 (10-mg tablets), lactose, starch, stearic acid, and sucrose.
Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.