ProHIBiT®, Haemophilus b Conjugate Vaccine (Diphtheria Toxoid-Conjugate),
for intramuscular use, is a sterile solution, prepared from the purified capsular
polysaccharide, a polymer of ribose, ribitol and phosphate (PRP) of the Eagen
Haemophilus influenzae type b strain covalently bound to diphtheria toxoid
(D) and dissolved in sodium phosphate buffered isotonic sodium chloride solution.
The polysaccharide-protein conjugate molecule is referred to as PRP-D. Thimerosal
(mercury derivative) 1:10,000 is added as a preservative. The vaccine is a clear,
colorless solution. Each single dose of 0.5 mL is formulated to contain 25 µg
of purified capsular polysaccharide and 18 µg of diphtheria toxoid protein.
Last reviewed on RxList: 3/9/2009
This monograph has been modified to include the generic and brand name in many instances.