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HYCOTUSS®
(hydrocodone bitartrate and guaifenesin) Expectorant Syrup

DRUG DESCRIPTION

HYCOTUSS (hydrocodone bitartrate and guaifenesin) Expectorant Syrup contains hydrocodone (dihydrocodeinone) bitartrate, a semi-synthetic centrally-acting opioid antitussive and guaifenesin, an expectorant for oral administration.

Chemically, Hydrocodone Bitartrate is 4, 5α-epoxy-3-methoxy-17-methyl-morphinan-6-one tartrate (1:1) hydrate (2:5) with the following structure:

Hydrocodone bitartrate Structural Formula Illustration

Chemically, Guaifenesin is 3-(o-methoxyphenoxy)-1, 2-propanediol with the following structure:

Guaifenesin Structural Formula Illustration

Each teaspoonful (5 mL) contains:

Hydrocodone bitartrate, USP......................5 mg
Guaifenesin, USP......................100 mg
Alcohol, USP 1...................... 0% v/v

Inactive Ingredients: FD&C Red No. 40, FD&C Yellow No. 6 (Sunset Yellow), flavoring, glycerin, methylparaben, propylparaben, purified water, sodium saccharin, sorbitol solution, and sucrose.

Last reviewed on RxList: 9/11/2008
This monograph has been modified to include the generic and brand name in many instances.