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ISUPREL
(isoproterenol hydrochloride) Injection, Solution
Sterile Injection 1:5000

DRUG DESCRIPTION

Isoproterenol hydrochloride is 3,4-Dihydroxy-a-[(isopropylamino)methyl] benzyl alcohol hydrochloride, a synthetic sympathomimetic amine that is structurally related to epinephrine but acts almost exclusively on beta receptors. The molecular formula is C11H17NO3• HCl. It has a molecular weight of 247.72 and the following structural formula:

Isuprel (isoproterenol hydrochloride) Structural Formula Illustration

Isoproterenol hydrochloride is a racemic compound.

Each milliliter of the sterile 1:5000 solution contains:

ISUPREL®, brand of isoproterenol hydrochloride injection, USP 0.2 mg

Lactic Acid 0.12 mg

Sodium Chloride 7.0 mg

Sodium Lactate 1.8 mg

Sodium Metabisulfite 1.0 mg

Water for Injection qs ad 1.0 mL

The pH is adjusted between 2.5 and 4.5 with hydrochloric acid.

The sterile 1:5000 solution is nonpyrogenic and can be administered by the intravenous, intramuscular, subcutaneous, or intracardiac routes.

What are the possible side effects of isoproterenol inhalation (Isuprel Mistometer)?

If you experience any of the following serious side effects, stop using isoproterenol inhalation and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
  • chest pain or an irregular heartbeat.

Other, less serious side effects may be more likely to occur. Continue to use isoproterenol inhalation and talk to your doctor if you experience

  • headache, dizziness, lightheadedness, or...

Read All Potential Side Effects and See Pictures of Isuprel »

Last reviewed on RxList: 6/11/2012
This monograph has been modified to include the generic and brand name in many instances.