Ocriplasmin is a recombinant truncated form of human plasmin
with a molecular weight of 27.2 kD a produced by recombinant DNA technology in
a Pichia pastoris expression system.
JETREA is a sterile, clear and colorless solution with no
preservatives in a single-use glass vial containing 0.5 mg ocriplasmin in 0.2
mL solution for intravitreal injection after dilution.
Each vial contains 0.5 mg ocriplasmin (active) and 0.21 mg
citric acid, 0.75 mg mannitol, sodium hydroxide (for pH adjustment) and water
for injection. The pH of the solution is 3.1.
Last reviewed on RxList: 10/30/2012
This monograph has been modified to include the generic and brand name in many instances.