VIOKACE is a pancreatic enzyme preparation for oral administration consisting
of pancrelipase, an extract derived from porcine pancreatic glands. Pancrelipase
contains multiple enzyme classes, including porcine-derived lipases, amylases,
Pancrelipase is a beige-white amorphous powder. It is miscible in water and
practically insoluble in alcohol.
The active ingredient evaluated in clinical trials is lipase. VIOKACE is dosed
by lipase units.
Other active ingredients include protease and amylase.
Inactive ingredients in VIOKACE include: colloidal silicon dioxide, crosscarmellose
sodium, lactose monohydrate, microcrystalline cellulose, stearic acid and talc.
10,440 USP units of lipase; 39,150 USP units of protease; 39,150 USP
units of amylase tablets are tan, round biconvex and have VIO9111 engraved on
one side and 9111 on the other side.
20,880 USP units of lipase; 78,300 USP units of protease; 78,300 USP
units of amylase tablets are tan, oval, biconvex with V16 engraved on one side
and 9116 on the other side.
What are the possible side effects of pancrelipase?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have severe or unusual stomach pain. This could be a symptom of a rare but serious bowel disorder.
Less serious side effects may include:
- nausea or vomiting;
- mild stomach pain or upset;
- diarrhea or constipation;
- bloating or gas.
- greasy stools;
- rectal irritation;
- headache, dizziness;
- cough; or
Read All Potential Side Effects and See Pictures of Viokace »
Last reviewed on RxList: 3/12/2012
This monograph has been modified to include the generic and brand name in many instances.