Podofilox (podofilox) Topical Solution is an antimitotic drug which can be chemically synthesized or purified from the plant families Coniferae and Berberidaceae (e.g.species of Juniperus and podophyllum). Podofilox (podofilox) Topical Solution 0.5% is formulated for topical administration. Each milliliter of solution contains 5 mg of podofilox (podofilox) , in a vehicle containing lactic acid and sodium lactate in alcohol 95%,USP.
Podofilox (podofilox) has a molecular weight of 414.4 daltons, and is soluble in alcohol and sparingly soluble in water. Its chemical name is 5,8,8a,9-Tetrahydro-9- hydroxy-5-(3,4,5- trimethoxylphenyl)furo[3†,4†:6,7] naphtho[2,3,d]-1, 3-diox- ol-6(5aH)-one.
Last reviewed on RxList: 6/14/2005
This monograph has been modified to include the generic and brand name in many instances.