EDURANT (rilpivirine) is a non-nucleoside reverse
transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1).
EDURANT is available as a white to off-white, film-coated, round, biconvex, 6.4
mm tablet for oral administration. Each tablet contains 27.5 mg of rilpivirine
hydrochloride, which is equivalent to 25 mg of rilpivirine.
The chemical name for rilpivirine hydrochloride is
monohydrochloride. Its molecular formula is C22H18N6
• HCl and its molecular weight is 402.88. Rilpivirine hydrochloride has the
following structural formula:
Rilpivirine hydrochloride is a
white to almost white powder. Rilpivirine hydrochloride is practically
insoluble in water over a wide pH range.
Each EDURANT tablet also
contains the inactive ingredients croscarmellose sodium, lactose monohydrate,
magnesium stearate, polysorbate 20, povidone K30 and silicified
microcrystalline cellulose. The tablet coating contains hypromellose 2910 6
mPa.s, lactose monohydrate, PEG 3000, titanium dioxide and triacetin.
Last reviewed on RxList: 1/2/2013
This monograph has been modified to include the generic and brand name in many instances.