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SKELAXIN®
(metaxalone) Tablets

DRUG DESCRIPTION

SKELAXIN® (metaxalone) is available as an 800 mg oval, scored pink tablet.

Chemically, metaxalone is 5-[(3,5- dimethylphenoxy) methyl]-2-oxazolidinone. The empirical formula is C12H15N03, which corresponds to a molecular weight of 221.25. The structural formula is:

SKELAXIN (metaxalone) structural formula illustration

Metaxalone is a white to almost white, odorless crystalline powder freely soluble in chloroform, soluble in methanol and in 96% ethanol, but practically insoluble in ether or water. Each tablet contains 800 mg metaxalone and the following inactive ingredients: alginic acid, ammonium calcium alginate, B-Rose Liquid, corn starch, and magnesium stearate.

What are the possible side effects of metaxalone (Skelaxin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using metaxalone and call your doctor at once if you have any of these serious side effects:

  • nausea, stomach pain, loss of appetite;
  • low fever;
  • dark urine, clay-colored stools; or
  • jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • drowsiness, dizziness;
  • feeling nervous or irritable;
  • headache;
  • mild nausea,...

Read All Potential Side Effects and See Pictures of Skelaxin »

What are the precautions when taking metaxalone (Skelaxin)?

Before taking metaxalone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, anemia, seizures.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal...

Read All Potential Precautions of Skelaxin »

Last reviewed on RxList: 11/8/2010
This monograph has been modified to include the generic and brand name in many instances.